Autonomic dysfunction: a novel neurological phenotype associated with Zika virus infection?

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Neurological manifestations of Zika virus infection

Zika virus (ZIKV) is a flavivirus (Flaviviridae family) transmitted mainly by Aedes mosquitoes. The virus was restricted to the African continent until its spread to south-east Asia in the 1980's, the Micronesia in 2007, the French Polynesia in 2013 and, more recently in the Americas in 2015, where, up to date, the World Health Organization (WHO) has estimated about 3-4 million total cases of Z...

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Zika Virus Infection Associated With Severe Thrombocytopenia.

We report two patients that developed severe thrombocytopenia after Zika virus (ZIKV) infection. The first patient had 1000 platelets/μL and died after multiple hemorrhages. The second patient had 2000 platelets/μL, had melena and ecchymoses, and recovered after receiving intravenous immunoglobulin. ZIKV may be associated with immune-mediated severe thrombocytopenia.

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ژورنال

عنوان ژورنال: Clinical Autonomic Research

سال: 2018

ISSN: 0959-9851,1619-1560

DOI: 10.1007/s10286-018-0516-0